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Abbas Alnaji

Alsadir Teaching Hospital, Iraq

Title: Cefixime and Azothromycin are beneficial in uncontrolled seizures in pediatric age group with or without mental retardation

Biography

Biography: Abbas Alnaji

Abstract

According to what had been mentioned in an article to the conference of Epilepsy and treatment 2015 USA, which is due the whole issue of the epilepsies or seizures to a specific type of chronic active bacterial global encephalitis CABGE, in our study it was mostly due to Neurobrucellosis, however other bacteria did not excluded and we recommended wider screening especially to those of intracellular nature. This combination was tailored due to Doxycyclin is not preferred in those of less than six of age. It has been choosed from several regimens were used by us as a trial treatment for what can be chronic Brucellosis patients diagnosed on clinical basis only to hinder emergence of antibiotics resistance in long term eradication efforts which exceeds that of complicated Tb in the old days.  Mental retardation in some of patients was the event which followed the phase of uncontrolled attacks in presence of the classical antiepileptics both quantitatively and qualitatively. The old or traditional teachings due this brain dysfunction to the cerebral trauma from repeated fits as anoxia or so. While, however it is correct, the major or the real event behind this mental retardation in our vision is the ongoing parenchyma destruction by the infective agent, where if this hypothesis is correct! (we say hypothesis in spite of presence of vast number of successfully treated patients +/- PCR results), antiepileptics do not stop destruction, and this explains why incremental doses of antiepileptics are needed like analgesics in headache.    This can be considered as a trial treatment based on clinical facts plus some PCR positive cases to reveal the cause behind abnormal cerebral electric discharge. The nomenclatures as idiopathic, post traumatic and so the other conditions are precipitating or a triggering factors.