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Jera Kruja

Jera Kruja

University of Medicine Tirana, Albania

Title: Depression and Epilepsy

Biography

Biography: Jera Kruja

Abstract

Background: Epilepsy is a chronic neurological disorders often complicated not only by recurrent seizures, but also from mood disorders. Nevertheless, mental health, including depression, is not routinely being assessed in patients diagnosed with epilepsy. Up to date, no former study has assessed the prevalence and severity of depression among epilepsy patients in Albania.

Methods: Twenty-nine (29) consecutive epilepsy outpatients were enrolled at the University Hospital Center “Mother Theresa” together with 47 healthy controls. To assess depression, both patients and controls were interviewed by trained neurologists using the Beck depression inventory II (BDI-II). Differences were tested using the independent samples t-test for total BDI-II scores, and chi-squared test for categorical levels of depression.

Results: Epilepsy patients (55.2% males, mean age 36.9 years old) showed no statistically significant gender or age difference with the healthy controls (55.3% males, mean age 42.1 years old). Nevertheless, epilepsy patients scored higher than controls on the BDI-II (mean score 16.4 versus 8.3, p<0.001). In epilepsy patients, prevalence of minimal, mild, moderate and severe depression were 48.3%, 20.7%, 20.7% and 10.3% respectively, showing a more severe distribution of depression levels (Pearson chi-square 8.914, p=0.03) compared to controls, which showed minimal, mild, moderate and severe depression in 80.8%, 8.5%, 6.4% and 4.3% of the cases respectively.

Conclusions: This study depicts, for the first time, the double burden of depression and epilepsy in Albanian patients, recognizing a higher prevalence and severity of depression in epilepsy. Therefore, in order for the need of mental health care to be met, a more careful and patient-oriented treatment strategy may be warranted.