Epilepsy Therapeutics & Drug therapy
Majorly epilepsy is treated with antiepileptic drugs primarily first line drugs like carbamazepine, valproate, phenytoin, carbazepine whereas, second generation include zonisamide and lacosamide are showing good efficacy with low adverse effects. Ethosuximide is majorly used for primary treatment. Diazepam is now available as rectal gel so that can be applied by family members for prolonged seizures. Drug combination sometimes lead to adverse effects like fatigue and loss of appetite so, combinations are often replaced by monotherapy unless monotherapy achieves desired results. When medication doesn’t achieve the required targets doctor can sometimes suggest for surgery 64% cases showed seizure free cases who undergone surgery.